| Addison-Wesley | book publisher, publishing house | 1942 |
| Advent International | business, private equity firm | 1984 |
| Arctic Coal Company | mining company | 1906 |
| Au Bon Pain | business | 1978 |
| Bain & Company | management consulting company | 1973 |
| Boston Beer Company | brewery, public company | 1985 |
| Cabot Corporation | business, public company | 1882 |
| Circle | dot-com company, business | October 2013 |
| Credo Reference | business | 1999 |
| Houghton Mifflin Harcourt | book publisher, publishing house, public company | 1880 |
| Institute of Contemporary Art, Boston | art gallery, nonprofit organization, art museum | 1936 |
| Irrational Games | video game developer | 1997 |
| John Hancock Insurance | business | 1862 |
| Massachusetts Bay Transportation Authority | public transport network, transport company | 1964 |
| MFS Investment Management | business | 1924 |
| New Balance | business, subsidiary company | 1906 |
| Northeast Airlines | airline | 1931 |
| Northeastern University | private not-for-profit educational institution, university | 1898 |
| State Street Corporation | global systemically important bank, business, enterprise, credit institution, public company | 1792 |
| Vertex Pharmaceuticals | pharmaceutical company, organization, business, public company | 1989 |
| Vic Firth Company | business, musical instrument manufacturing company | 1963 |
| WHOOP | business | — |
| Ximian | business, enterprise | October 19, 1999 |