| American Academy of Arts and Sciences | nonprofit organization, learned society, academic publisher | May 4, 1780 |
| Biogen | biopharmaceutical company, business, public company | 1978 |
| Forrester | business, public company | 1983 |
| Genzyme | business, subsidiary company, enterprise | 1981 |
| Harmonix Music Systems | video game developer | 1995 |
| John F. Kennedy School of Government | public policy school, graduate school, private school | 1936 |
| Looking Glass Studios | video game developer | 1990 |
| Lotus Software | business | 1982 |
| MIT Media Lab | faculty, university research group | 1985 |
| Moderna | biopharmaceutical company, business, public company | 2010 |
| Pegasystems | business, public company | 1983 |
| The MIT Press | book publisher, open-access publisher, university press, academic publisher | 1932 |