| Midway Games | video game developer, business, enterprise, public company | Chicago | 1988 |
| Monolith Productions | publishing house, video game developer | Kirkland | October 25, 1994 |
| Monster Games | video game developer | Northfield | 1996 |
| Mythic Entertainment | video game developer | Fairfax | 1995 |
| Naughty Dog | video game developer | Santa Monica | 1984 |
| Nintendo Software Technology | video game developer | Redmond | 1998 |
| NovaLogic | video game developer | Agoura Hills | 1985 |
| NStigate Games | video game developer | Marin County | March 1998 |
| Origin Systems | video game publisher, video game developer | Austin | 1983 |
| Panic | video game publisher, video game developer, business | Portland, Oregon | — |
| Petroglyph Games | video game publisher, video game developer | Las Vegas | April 1, 2003 |
| Pi Studios | video game developer | Houston | 2002 |
| Private Division | video game publisher | New York City | December 14, 2017 |
| Raven Software | video game developer | Middleton, Madison | 1990 |
| Razer Inc. | privately held company, business, public company | George Town, Singapore, Carlsbad, Irvine, San Francisco | 1998 |
| Red Orb Entertainment | business | Novato | 1997 |
| Renegade Kid | video game publisher, video game developer | Austin | 2007 |
| Ritual Entertainment | video game developer | Dallas | 1996 |
| Roblox Corporation | video game developer, business, public company | San Mateo | 2004 |
| Rockstar Games | video game publisher | New York City | December 1998 |
| Rockstar New England | video game developer | Andover | 1999 |
| Saber Interactive | video game developer | Fort Lauderdale, Minsk, Sundsvall, Porto, Millburn, Community of Madrid, Saint Petersburg, Florida | 2001 |
| Santa Monica Studio | video game developer | Playa Vista | 1999 |
| Sekai Project | video game publisher, business | Norwalk, Los Angeles | 2007 |
| Shaba Games | business | San Francisco | 1997 |
| Shiny Entertainment | video game developer, business | Laguna Beach, Newport Beach | 1993 |
| Sledgehammer Games | video game developer | Foster City | 2009 |
| Strategic Simulations | video game publisher, video game developer, business, enterprise | Sunnyvale | 1979 |
| Sucker Punch Productions | video game developer | Bellevue | October 1997 |
| Supergiant Games | video game publisher, video game developer | San Jose | 2009 |
| TalonSoft | video game publisher, video game developer | Baltimore | 1995 |
| Tandy Corporation | video game publisher, trading company | Fort Worth | 1919 |
| Telltale Games | video game publisher, video game developer, business, independent business, enterprise | San Rafael | July 2004 |
| Tengen | video game publisher, video game developer | Milpitas | 1987 |
| THQ | video game publisher, video game developer, public company | Agoura Hills, California | 1990 |
| Tiger Electronics | business, subsidiary company | Vernon Hills | 1978 |
| Tilted Mill Entertainment | video game developer | Framingham | 2001 |
| Toys for Bob | video game developer | Novato | 1989 |
| Tripwire Interactive | video game developer | Roswell | 2005 |
| Troika Games | video game developer, organization | Irvine | 1998 |
| Turtle Beach Systems | business, public company | Valhalla | 1975 |
| Undead Labs | business | Seattle | November 23, 2009 |
| Viz Media, LLC | publishing house, business, company | San Francisco | 1984 |
| Volition | video game developer | Champaign | November 1996 |
| Warner Bros. Entertainment | film production company, entertainment company | Burbank | April 4, 1923 |
| Warner Bros. Games | video game publisher, video game developer | Burbank | January 2004 |
| WB Games Boston | video game developer | Westwood | 1994 |
| Westwood Studios | video game developer, business | Las Vegas | 1992 |