| American Cyanamid | business | Wayne | 1907 |
| Amgen | biopharmaceutical company, business, enterprise, public company | Thousand Oaks | 1980 |
| Bausch & Lomb | organization, business, enterprise, public company | Vaughan, Rochester | 1853 |
| Biogen | biopharmaceutical company, business, public company | Cambridge | 1978 |
| Celgene | pharmaceutical company, business, enterprise, public company | Summit | 1986 |
| Cencora | business, enterprise, public company | Chesterbrook | 2001 |
| Genzyme | business, subsidiary company, enterprise | Cambridge | 1981 |
| Incyte | business, enterprise, public company | Wilmington | 2001 |
| IQVIA Holdings, Inc. | business, enterprise, contract research organization, public company | Danbury, Durham | 2016 |
| Moderna | biopharmaceutical company, business, public company | Cambridge | 2010 |
| Organon & Co. | organization, business, public company | Oss | 1923 |
| Regeneron Pharmaceuticals | business, public company | Eastview | 1988 |
| Vertex Pharmaceuticals | pharmaceutical company, organization, business, public company | Boston | 1989 |
| Viatris | multinational corporation, pharmaceutical company, public company | Pittsburgh | November 2020 |