| Access Systems Americas | business | Reston | — |
| Adobe | software company, type foundry, business, data controller, enterprise, public company | San Jose | February 28, 1982 |
| Apple Inc. | corporation, technology company, business, enterprise, public company | Cupertino | April 1, 1976 |
| Automatic Data Processing | software company, business, enterprise, public company, accounting software | Roseland | 1949 |
| Bell Labs | privately held company, publishing house, research institute | Murray Hill | 1925 |
| BlueStacks | business | — | 2011 |
| CodeGear | business, enterprise | Scotts Valley, California | 2006 |
| Cygnus Solutions | business | — | November 13, 1989 |
| Dell EMC | business, enterprise, public company | Hopkinton | August 1979 |
| E-mu Systems | business, musical instrument manufacturing company | Scotts Valley | 1971 |
| EnterpriseDB | business | Bedford | March 2004 |
| Genesys | business, enterprise | Daly City | 1990 |
| Intetics | software company | Naples | 1995 |
| Jasc Software | business | Eden Prairie | 1990 |
| Logitech | software company, technology company, brand, business, public company | Lausanne, Newark | October 2, 1981 |
| Lotus Software | business | Cambridge | 1982 |
| Macromedia | business, enterprise | San Francisco | February 25, 1992 |
| Narus | business, software | Sunnyvale | 1997 |
| NetSuite | business, enterprise, public company | Austin | 1998 |
| NeXT | business, enterprise | Palo Alto, Redwood City | June 20, 1985 |
| Palm, Inc. | business, enterprise | Sunnyvale | 1992 |
| Pandora | music streaming service, website, organization, recommender system, online music database, public company | Oakland | January 2000 |
| Panic | video game publisher, video game developer, business | Portland, Oregon | — |
| Parallels | business, enterprise | Renton | 1999 |
| Pegasystems | business, public company | Cambridge | 1983 |
| Perforce Zend | brand, business, enterprise | Minneapolis | 1999 |
| Qlik | privately held company, business, enterprise, public company | King of Prussia | 1993 |
| Quest Software | business | Aliso Viejo | 1987 |
| RealNetworks | privately held company, business, enterprise | Seattle | 1993 |
| SoundHound | music recognition software, enterprise, public company | Santa Clara | September 2005 |
| Squarespace | commercial organization, public company | New York City | 2003 |
| Strategy | software company, business, public company | Tysons | 1989 |
| Synopsys | business, enterprise, public company | Mountain View | 1986 |
| TopCoder | business, enterprise | San Francisco | 2001 |
| Twilio | website, business, company, public company | San Francisco | 2008 |
| Wrike Inc. | business | Mountain View | 2006 |
| Ximian | business, enterprise | Boston | October 19, 1999 |
| Zendesk | software company, technology company, business, public company | San Francisco | 2007 |