| Warner Bros. Cartoons | Burbank, Los Angeles | November 10, 1926 |
| Warner Bros. Discovery | New York City | April 8, 2022 |
| Warner Bros. Home Entertainment | Burbank | 2023 |
| WarnerMedia | Delaware, New York City | 2016 |
| Warrior Sports | Warren | 1992 |
| Washington Open | — | 1969 |
| Waste Management, Inc | Houston | 1968 |
| Waterman | Paris | 1883 |
| Waters Corporation | Milford | 1958 |
| Weatherby | Sheridan, Paso Robles | 1945 |
| Webex by Cisco | Milpitas | 1995 |
| Wells Fargo | San Francisco | March 18, 1852 |
| Western Digital | San Jose | April 23, 1970 |
| Western Pacific Railroad | San Francisco | 1916 |
| Westwood Studios | Las Vegas | 1992 |
| WeWork | Manhattan, New York | 2010 |
| Weyerhaeuser | Seattle, Federal Way | 1900 |
| Whirlpool Corporation | Benton Harbor | November 11, 1911 |
| White Motor Company | Cleveland | 1902 |
| White Wolf Publishing | Stone Mountain | December 1990 |
| WHOOP | Boston | — |
| William B. Eerdmans Publishing Company | Grand Rapids | 1911 |
| Wilson Sporting Goods | Chicago | 1913 |
| Winchester Repeating Arms Company | New Haven | 1866 |
| Wind River Systems | Alameda, California | 1981 |
| Wingstop | Dallas | 1994 |
| Winnebago Industries | Eden Prairie | February 12, 1958 |
| Winton Motor Carriage Company | Cleveland | 1897 |
| Wish.com | San Francisco | 2010 |
| WME Group | Beverly Hills | 1898 |
| Woot | Carrollton | 2004 |
| Workhorse Group | Cincinnati, Sharonville | 1998 |
| World Championship Wrestling | Atlanta | October 11, 1988 |
| World Class Championship Wrestling | Dallas | 1966 |
| Wrangler | Greensboro | 1904 |
| Wrigley Company | Chicago | April 1, 1891 |
| Wrike Inc. | Mountain View | 2006 |
| WSP Global | Montreal | 1959 |
| WW International | New York City | 1963 |
| WWE | Stamford | 1952 |
| WWE Performance Center | Orlando | July 11, 2013 |
| Wynn Resorts | Las Vegas | 2002 |
| X Corp. | Bastrop | March 9, 2023 |
| XCOR Aerospace | Mojave Air and Space Port at Rutan Field | September 1999 |
| XFX | Ontario, California | 1989 |
| Ximian | Boston | October 19, 1999 |
| XPO, Inc. | Greenwich | 1987 |
| Yahoo Inc. | Sunnyvale, New York City | 2006 |