| Universal Studios Hollywood | theme park | — | 1964 |
| Universal Studios Home Entertainment | media distributor | Universal City | 1979 |
| University at Buffalo | public educational institution of the United States, open-access publisher, census-designated place in the United States, public research university | Amherst | 1846 |
| University of Alabama | public educational institution of the United States, public university | Tuscaloosa | 1831 |
| University of Alabama at Birmingham | public educational institution of the United States, public research university | — | 1969 |
| University of Alabama in Huntsville | public educational institution of the United States, university | — | 1950 |
| University of Alaska Fairbanks | public educational institution of the United States, land-grant university, public university | College | 1917 |
| University of Alaska System | state university system | Fairbanks | 1917 |
| University of Arkansas | public educational institution of the United States, land-grant university, public research university | Fayetteville | 1871 |
| University of Arkansas for Medical Sciences | medical university, public educational institution of the United States | — | 1879 |
| University of Austin | private not-for-profit educational institution, university | — | — |
| University of Baltimore | public educational institution of the United States, public university | Baltimore | 1925 |
| University of California College of the Law, San Francisco | law school, public educational institution of the United States, university, academic publisher | — | 1878 |
| University of California, Berkeley School of Law | law school | — | 1894 |
| University of California, Los Angeles | public educational institution of the United States, public research university | Los Angeles | May 23, 1919 |
| University of California, San Diego | public educational institution of the United States, public university | — | November 18, 1960 |
| University of Central Missouri | public educational institution of the United States, university | — | 1871 |
| University of Chicago Press | book publisher, university press | Chicago | 1891 |
| University of Cincinnati | public educational institution of the United States, public research university | — | 1819 |
| University of Colorado | university | Denver | 1876 |
| University of Colorado Colorado Springs | public educational institution of the United States, university | — | 1965 |
| University of Georgia | university | Old North Campus | 1785 |
| University of Hawaii Press | open-access publisher, university press | Honolulu | 1947 |
| University of Hawaiʻi at Hilo | public educational institution of the United States, university | — | 1941 |
| University of Hawaiʻi at Mānoa | public educational institution of the United States, land-grant university, public university | — | 1907 |
| University of Hawaiʻi–West Oʻahu | public educational institution of the United States, university | Kapolei | 1976 |
| University of Illinois Chicago | public educational institution of the United States, open-access publisher, public university | — | January 1983 |
| University of Illinois Press | book publisher, university press | Champaign | 1918 |
| University of Illinois Springfield | public educational institution of the United States, university | — | 1969 |
| University of Illinois Urbana-Champaign | public educational institution of the United States, land-grant university, public research university | — | 1867 |
| University of Kentucky | public educational institution of the United States, open-access publisher, land-grant university, public university | Lexington | 1865 |
| University of Louisiana at Monroe | public educational institution of the United States, university | — | 1931 |
| University of Louisville | public educational institution of the United States, public research university | Louisville | 1798 |
| University of Maryland | publishing house, public educational institution of the United States, land-grant university, public research university | College Park | 1856 |
| University of Maryland, Baltimore County | research university, public educational institution of the United States, university | — | 1966 |
| University of Massachusetts Amherst | public educational institution of the United States, university, land-grant university | Amherst | 1863 |
| University of Massachusetts Boston | public educational institution of the United States, university | Dorchester | 1964 |
| University of Memphis | public educational institution of the United States, public research university | — | 1912 |
| University of Miami | private not-for-profit educational institution, university | Coral Gables | 1925 |
| University of Michigan Law School | law school | — | 1859 |
| University of Michigan Press | open-access publisher, university press | Ann Arbor | 1930 |
| University of Minnesota Press | publishing house, university press | Minneapolis | 1925 |
| University of Missouri–Kansas City | public educational institution of the United States, public university | — | 1933 |
| University of Montana | research university, public educational institution of the United States, public university | — | 1893 |
| University of Nebraska Omaha | public educational institution of the United States, public university | — | 1908 |
| University of Nebraska system | state university system | Lincoln | 1850 |
| University of Nevada, Las Vegas | public educational institution of the United States, public research university | Las Vegas | September 10, 1957 |
| University of Nevada, Reno | public educational institution of the United States, land-grant university, public research university | Reno | 1874 |